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Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications Обзор

Журнал International Journal of Molecular Sciences
ISSN: 1661-6596 , E-ISSN: 1422-0067
Вых. Данные Год: 2023, Том: 24, Номер: 3, Страницы: 2937-2937 Страниц : 1 DOI: 10.3390/ijms24032937
Авторы Frolov Nikita A. 1 , Vereshchagin Anatoly N. 1
Организации
1 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia

Реферат: Piperidines are among the most important synthetic fragments for designing drugs and play a significant role in the pharmaceutical industry. Their derivatives are present in more than twenty classes of pharmaceuticals, as well as alkaloids. The current review summarizes recent scientific literature on intra- and intermolecular reactions leading to the formation of various piperidine derivatives: substituted piperidines, spiropiperidines, condensed piperidines, and piperidinones. Moreover, the pharmaceutical applications of synthetic and natural piperidines were covered, as well as the latest scientific advances in the discovery and biological evaluation of potential drugs containing piperidine moiety. This review is designed to help both novice researchers taking their first steps in this field and experienced scientists looking for suitable substrates for the synthesis of biologically active piperidines.
Библиографическая ссылка: Frolov N.A. , Vereshchagin A.N.
Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications
International Journal of Molecular Sciences. 2023. V.24. N3. P.2937-2937. DOI: 10.3390/ijms24032937 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:000930402400001
Scopus: 2-s2.0-85147895102
OpenAlex: W4319083600
Цитирование в БД:
БД Цитирований
OpenAlex 76
Scopus 51
Web of science 76
Альметрики: