Photoredox Catalyzed Dealkylative Aromatic Halogen Substitution with Tertiary Amines

Photoredox Catalyzed Dealkylative Aromatic Halogen Substitution with Tertiary Amines Full article

Journal

Molecules
ISSN: 1420-3049

Output data

Year: 2021, Volume: 26, Number: 11, Article number : 3323, Pages count : DOI: 10.3390/molecules26113323

Authors

Lipilin Dmitry L. ¹ , Frumkin Alexander E. ¹ , Tyurin Alexey Y. ¹ , Levin Vitalij V. ¹ , Dilman Alexander D. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Leninsky Prosp. 47, 119991 Moscow, Russia.

A reaction of aromatic halides bearing electron-withdrawing groups with tertiary amines in the presence of an iridium catalyst under blue light irradiation is described. Products of the aromatic substitution of the halide by the dialkylamino fragment are obtained. The interaction of aryl radicals with tertiary amines to generate zwitterionic radical species is believed to be the key factor responsible for the reaction efficiency.

Lipilin D.L. , Frumkin A.E. , Tyurin A.Y. , Levin V.V. , Dilman A.D.
Photoredox Catalyzed Dealkylative Aromatic Halogen Substitution with Tertiary Amines
Molecules. 2021. V.26. N11. 3323 . DOI: 10.3390/molecules26113323 WOS Scopus OpenAlex

Web of science:	WOS:000660441000001
Scopus:	2-s2.0-85108000028
OpenAlex:	W3170380266

DB	Citing
OpenAlex	4
Scopus	4