Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives

Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives Научная публикация

Журнал

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Вых. Данные

Год: 2021, Том: 31, Номер: 3, Страницы: 368-369 Страниц : 2 DOI: 10.1016/j.mencom.2021.05.028

Авторы

Vereshchagin Anatoly N. ¹ , Frolov Nikita A. ¹ , Minaeva Alexandra P. ^2,1 , Detusheva Elena V. ³ , Derkach Yana V. ^2,1 , Egorov Mikhail P. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
2	D. I. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russian Federation
3	State Research Center for Applied Microbiology & Biotechnology, 142279 Obolensk, Serpukhov District, Moscow Region, Russian Federation

Novel tris(4-alkylaminopyridin-1-ium) trichlorides with alkylcyanuric spacer were synthesized by quaternization of 4-alkylaminopyridines with tris(2-chloroethyl) cyanurate. The obtained compounds were evaluated for microbiological activity against five pathogenic bacterial strains (Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Acinobacter baumannii, Pseudomonas aeruginosa). The results indicate the presence of pronounced antibacterial properties in this group of compounds.

Vereshchagin A.N. , Frolov N.A. , Minaeva A.P. , Detusheva E.V. , Derkach Y.V. , Egorov M.P.
Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives
Mendeleev Communications. 2021. V.31. N3. P.368-369. DOI: 10.1016/j.mencom.2021.05.028 WOS OpenAlex

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