Electrooxidative C–H Functionalization of Heteroarenes. Thiocyanation of Pyrazolo[1,5‐a]pyrimidines

Electrooxidative C–H Functionalization of Heteroarenes. Thiocyanation of Pyrazolo[1,5‐a]pyrimidines Full article

Journal

European Journal of Organic Chemistry
ISSN: 1434-193X , E-ISSN: 1099-0690

Output data

Year: 2019, Volume: 2019, Number: 26, Pages: 4233-4238 Pages count : 6 DOI: 10.1002/ejoc.201900390

Authors

Kokorekin Vladimir A. ^1,2 , Yaubasarova Rauza R. ¹ , Neverov Sergei V. ¹ , Petrosyan Vladimir A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russian Federation
2	Sechenov First Moscow State Medical University; Trubetskaya st. 8-2 119991 Moscow Russian Federation

Efficient electrooxidative C–H thiocyanation of both high and low reactive pyrazolo[1,5-a]pyrimidines using a new system of complementary approaches has been developed. Advantages of this promising strategy are the undivided cell, mild conditions, and readily available reagents as well as feasible scaling up process and transformation of the synthesized aryl thiocyanates to new thiols. Also, target thiocyanates were found to have pronounced antifungal activity.

Kokorekin V.A. , Yaubasarova R.R. , Neverov S.V. , Petrosyan V.A.
Electrooxidative C–H Functionalization of Heteroarenes. Thiocyanation of Pyrazolo[1,5‐a]pyrimidines
European Journal of Organic Chemistry. 2019. V.2019. N26. P.4233-4238. DOI: 10.1002/ejoc.201900390 WOS Scopus OpenAlex

≡ Web of science:	WOS:000475679400017
≡ Scopus:	2-s2.0-85066910523
≡ OpenAlex:	W2940721529