Synthetic Strategies for Peroxide Ring Construction in Artemisinin | Sciact

Synthetic Strategies for Peroxide Ring Construction in Artemisinin Обзор

Журнал

Molecules
ISSN: 1420-3049

Вых. Данные

Год: 2017, Том: 22, Номер: 1, Номер статьи : 117, Страниц : DOI: 10.3390/molecules22010117

Авторы

Vil Vera A ^1,2,3 , Yaremenko Ivan A ^1,2,3 , Ilovaisky Alexey I ³ , Terent'ev Alexander O ^1,2,3

Организации

1	All-Russian Research Institute for Phytopathology, 143050 B. Vyazyomy, Moscow Region, Russia
2	Faculty of Chemical and Pharmaceutical Technology and Biomedical Products, D. I. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Square, Moscow 125047, Russia
3	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Prospekt, Moscow 119991, Russia

The present review summarizes publications on the artemisinin peroxide fragment synthesis from 1983 to 2016. The data are classified according to the structures of a precursor used in the key peroxidation step of artemisinin peroxide cycle synthesis. The first part of the review comprises the construction of artemisinin peroxide fragment in total syntheses, in which peroxide artemisinin ring resulted from reactions of unsaturated keto derivatives with singlet oxygen or ozone. In the second part, the methods of artemisinin synthesis based on transformations of dihydroartemisinic acid are highlighted.

Vil V.A. , Yaremenko I.A. , Ilovaisky A.I. , Terent'ev A.O.
Synthetic Strategies for Peroxide Ring Construction in Artemisinin
Molecules. 2017. V.22. N1. 117 . DOI: 10.3390/molecules22010117 WOS Scopus OpenAlex

Web of science:	WOS:000395473500116
Scopus:	2-s2.0-85009470021
OpenAlex:	W2577808018

БД	Цитирований
OpenAlex	44
Scopus	28
Web of science	40