Proline-Histidine Dipeptide: A Suitable Template for Generating Ion-Tagged Organocatalysts for the Asymmetric Aldol Reaction

Proline-Histidine Dipeptide: A Suitable Template for Generating Ion-Tagged Organocatalysts for the Asymmetric Aldol Reaction Full article

Journal

Synthesis-Stuttgart
ISSN: 1437-210X , E-ISSN: 0039-7881

Output data

Year: 2021, Volume: 53, Number: 15, Pages: 2702-2712 Pages count : 11 DOI: 10.1055/a-1477-4871

Authors

Inani Heena ¹ , Singh Avtar ¹ , Bhati Meeta ¹ , Kumari Kiran ¹ , Kucherenko Alexander S. ² , Zlotin Sergei G. ² , Easwar Srinivasan ¹

Affiliations

1	Department of Chemistry, School of Chemical Sciences and Pharmacy, Central University of Rajasthan
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

Proline-histidine dipeptide laid the foundation for the construction of three new ion-tagged organocatalysts, utilising the imidazole moiety of histidine for generating the quaternary species. A brief comparative investigation of the catalysts in the enamine-mediated direct asymmetric aldol reaction brought out their contrasting features, particularly under aqueous conditions. The best among them was also utilised in preparing some derivatives and effecting a desymmetrisation.

Inani H. , Singh A. , Bhati M. , Kumari K. , Kucherenko A.S. , Zlotin S.G. , Easwar S.
Proline-Histidine Dipeptide: A Suitable Template for Generating Ion-Tagged Organocatalysts for the Asymmetric Aldol Reaction
Synthesis-Stuttgart. 2021. V.53. N15. P.2702-2712. DOI: 10.1055/a-1477-4871 WOS Scopus OpenAlex

Web of science:	WOS:000651583300001
Scopus:	2-s2.0-85106927968
OpenAlex:	W3154484696

DB	Citing
OpenAlex	5
Scopus	9
Web of science	5