New approach to the synthesis of substituted 7H‐furo[3,2‐b]pyran‐7‐ones based on 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one derivatives

New approach to the synthesis of substituted 7H‐furo[3,2‐b]pyran‐7‐ones based on 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one derivatives Full article

Journal

Journal of Heterocyclic Chemistry
ISSN: 0022-152X , E-ISSN: 1943-5193

Output data

Year: 2019, Volume: 56, Number: 11, Pages: 3081-3087 Pages count : 7 DOI: 10.1002/jhet.3706

Authors

Komogortsev Andrey N. ¹ , Lichitsky Boris V. ¹ , Tretyakov Alexander D. ¹ , Fakhrutdinov Artem N. ¹ , Dudinov Arkady A. ¹ , Krayushkin Michail M. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

A convenient approach to the synthesis of the previously unknown 7H-furo[3,2-b]pyran-7-ones based on the intramolecular cyclization of carbonyl derivatives of 5-hydroxy-2-methyl-4H-pyran-4-one has been elaborated. Key intermediates in the synthesis of the target 7H-furo[3,2-b]pyran-7-ones are 3-hydroxy-6-methyl-2-(2-oxo-2-arylethyl)-4H-pyran-4-ones. They are formed as a result of multicomponent condensation of 5-hydroxy-2-methyl-4H-pyran-4-one with arylglyoxals and 4-methoxyaniline.

Komogortsev A.N. , Lichitsky B.V. , Tretyakov A.D. , Fakhrutdinov A.N. , Dudinov A.A. , Krayushkin M.M.
New approach to the synthesis of substituted 7H‐furo[3,2‐b]pyran‐7‐ones based on 5‐hydroxy‐2‐methyl‐4H‐pyran‐4‐one derivatives
Journal of Heterocyclic Chemistry. 2019. V.56. N11. P.3081-3087. DOI: 10.1002/jhet.3706 WOS Scopus OpenAlex

Web of science:	WOS:000485076400001
Scopus:	2-s2.0-85071744558
OpenAlex:	W2971831692

DB	Citing
OpenAlex	15
Scopus	15
Web of science	15