Reductive Bromodifluoromethylation of Nitrones Promoted by Visible Light

Reductive Bromodifluoromethylation of Nitrones Promoted by Visible Light Full article

Journal

European Journal of Organic Chemistry
ISSN: 1434-193X , E-ISSN: 1099-0690

Output data

Year: 2019, Volume: 2019, Number: 26, Pages: 4119-4122 Pages count : 4 DOI: 10.1002/ejoc.201900274

Authors

Dmitriev Igor A. ^1,2 , Supranovich Vyacheslav I. ² , Levin Vitalij V. ² , Dilman Alexander D. ²

Affiliations

1	Moscow State University, Department of Chemistry, 119991 Moscow, Leninskie Gory 1-3, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation

A method for the synthesis of bromodifluoromethyl-substituted hydroxylamines via reaction of nitrones with dibromodifluoromethane is described. The reaction is mediated by an iridium photocatalyst activated by blue light and employs ascorbic acid as a reductant. In the products, the bromodifluoromethyl fragment can be reduced to the CHF2-group or can be functionalized through the hydrofluoroalkylation process.

Dmitriev I.A. , Supranovich V.I. , Levin V.V. , Dilman A.D.
Reductive Bromodifluoromethylation of Nitrones Promoted by Visible Light
European Journal of Organic Chemistry. 2019. V.2019. N26. P.4119-4122. DOI: 10.1002/ejoc.201900274 WOS Scopus OpenAlex

Web of science:	WOS:000475679400003
Scopus:	2-s2.0-85063681368
OpenAlex:	W2924599459

DB	Citing
OpenAlex	12
Scopus	13