A new facile method for the synthesis of 3-imidazolylpropionic acid N-oxides | Sciact

A new facile method for the synthesis of 3-imidazolylpropionic acid N-oxides Научная публикация

Журнал

Chemistry of Heterocyclic Compounds
ISSN: 1573-8353 , E-ISSN: 0009-3122

Вых. Данные

Год: 2019, Том: 55, Номер: 2, Страницы: 147-155 Страниц : 9 DOI: 10.1007/s10593-019-02431-7

Авторы

Kutasevich Anton V. ¹ , Perevalov Valery P. ¹ , Mityanov Vitaly S. ^1,2 , Lichitsky Boris V. ² , Komogortsev Andrey N. ² , Krayushkin Mikhail M. ² , Koldaeva Tatyana Yu. ¹ , Miroshnikov Vladimir S. ¹

Организации

1	Department of Fine Organic Synthesis and Chemistry of Dyes, D. I. Mendeleyev University of Chemical Technology of Russia, 9 Miusskaya Sq., Moscow 125047, Russia
2	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia

A facile and efficient method for the preparation of 3-imidazolylpropionic acid N-oxides has been developed. It involves condensation of 2-unsubstituted imidazole N-oxide with an aldehyde and Meldrum's acid followed by hydrolysis and decarboxylation of the corresponding adduct. This method tolerates a broad variation in the structure of starting aldehydes as well as N-oxides.

Kutasevich A.V. , Perevalov V.P. , Mityanov V.S. , Lichitsky B.V. , Komogortsev A.N. , Krayushkin M.M. , Koldaeva T.Y. , Miroshnikov V.S.
A new facile method for the synthesis of 3-imidazolylpropionic acid N-oxides
Chemistry of Heterocyclic Compounds. 2019. V.55. N2. P.147-155. DOI: 10.1007/s10593-019-02431-7 WOS Scopus OpenAlex

Web of science:	WOS:000463779400006
Scopus:	2-s2.0-85064010806
OpenAlex:	W2925257698

БД	Цитирований
OpenAlex	9
Scopus	10
Web of science	10