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Bioactive Natural and Synthetic Peroxides for the Treatment of Helminth and Protozoan Pathogens: Synthesis and Properties Review

Journal Current Topics in Medicinal Chemistry
ISSN: 1873-4294 , E-ISSN: 1568-0266
Output data Year: 2019, Volume: 19, Number: 14, Pages: 1201-1225 Pages count : 25 DOI: 10.2174/1568026619666190620143848
Authors Vil' Vera A. 1,2 , Terent'ev Alexander O. 1,2 , Mulina Olga M. 1,2
Affiliations
1 N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt 47, Moscow, 119991, Russian Federation
2 All-Russian Research Institute for Phytopathology, 143050, B. Vyazyomy, Moscow Region, Russian Federation

Abstract: The significant spread of helminth and protozoan infections, the uncontrolled intake of the known drugs by a large population, the emergence of resistant forms of pathogens have prompted people to search for alternative drugs. In this review, we have focused attention on structures and synthesis of peroxides active against parasites causing neglected tropical diseases and toxoplasmosis. To date, promising active natural, semi-synthetic and synthetic peroxides compounds have been found.
Cite: Vil' V.A. , Terent'ev A.O. , Mulina O.M.
Bioactive Natural and Synthetic Peroxides for the Treatment of Helminth and Protozoan Pathogens: Synthesis and Properties
Current Topics in Medicinal Chemistry. 2019. V.19. N14. P.1201-1225. DOI: 10.2174/1568026619666190620143848 WOS Scopus OpenAlex
Identifiers:
≡ Web of science: WOS:000483424100003
≡ Scopus: 2-s2.0-85072041721
≡ OpenAlex: W2950042693
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