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Highly oxygenated isoprenoid lipids derived from fungi and fungal endophytes: Origin and biological activities Обзор

Журнал Steroids
ISSN: 1878-5867 , E-ISSN: 0039-128X
Вых. Данные Год: 2018, Том: 140, Страницы: 114-124 Страниц : 11 DOI: 10.1016/j.steroids.2018.10.006
Авторы Savidov Nick 1 , Gloriozova Tatyana A. 2 , Poroikov Vladimir V. 2 , Dembitsky Valery M. 1,3,4
Организации
1 Centre for Applied Research and Innovation, Lethbridge College, 3000 College Drive South, Lethbridge AB T1K 1L6, Canada
2 Institute of Biomedical Chemistry, Moscow 119121, Russian Federation
3 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991, Russian Federation
4 National Scientific Center of Marine Biology, Vladivostok 690041, Russian Federation

Реферат: This mini review is devoted to highly oxygenated isoprenoid lipids (HOIL) that are produced by fungi and fungal endophytes from various ecological niches, both terrestrial and aquatic. Steroids were distributed as from edible cultivated fungi, as well as fungi collected in forests. Fungal endophytes were generally isolated from plants and cultured to obtain sufficient biomass. Marine fungi were obtained from marine brown and red algae and marine invertebrates such as sponges, corals, worms, crustacea or from marine sediments. HOIL isolated from the terrestrial ecosystem have the pharmacological potential on anti-hypercholesterolemic, anti-neoplastic, anti-eczematic and anti-inflammatory activity estimated with a confidence of 84–90%. HOIL that produced by marine fungal species are predicted as having anti-inflammatory and anti-hypercholesterolemic activity with a confidence of 82–91%. In addition, they may have potential acetylcholinesterase and cell adhesion molecule inhibitors estimated with a confidence of 86–88%.
Библиографическая ссылка: Savidov N. , Gloriozova T.A. , Poroikov V.V. , Dembitsky V.M.
Highly oxygenated isoprenoid lipids derived from fungi and fungal endophytes: Origin and biological activities
Steroids. 2018. V.140. P.114-124. DOI: 10.1016/j.steroids.2018.10.006 WOS Scopus OpenAlex
Идентификаторы БД:
≡ Web of science: WOS:000453337600015
≡ Scopus: 2-s2.0-85054872120
≡ OpenAlex: W2896319452
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