Pseudo six-component stereoselective synthesis of 2,4,6-triaryl-3,3,5,5-tetracyanopiperidines

Pseudo six-component stereoselective synthesis of 2,4,6-triaryl-3,3,5,5-tetracyanopiperidines Научная публикация

Журнал

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Вых. Данные

Год: 2018, Том: 28, Номер: 4, Страницы: 384-386 Страниц : 3 DOI: 10.1016/j.mencom.2018.07.014

Авторы

Vereshchagin Anatoly N. ¹ , Karpenko Kirill A. ¹ , Elinson Michail N. ¹ , Dorofeeva Evgeniya O. ¹ , Goloveshkin Alexander S. ² , Egorov Mikhail P. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
2	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 119991 Moscow, Russian Federation

The Knövenagel–Michael–Mannich cascade reaction of aromatic aldehyde (3 equiv.), malononitrile (2 equiv.) and ammonium acetate or aqueous ammonia provides convenient stereoselective access to cis,cis-2,4,6-triaryl-3,3,5,5-tetracyanopiperidines in 62–94% yields. Six new bonds form as a result of the domino process, ammonium acetate serving as a nitrogen source.

Vereshchagin A.N. , Karpenko K.A. , Elinson M.N. , Dorofeeva E.O. , Goloveshkin A.S. , Egorov M.P.
Pseudo six-component stereoselective synthesis of 2,4,6-triaryl-3,3,5,5-tetracyanopiperidines
Mendeleev Communications. 2018. V.28. N4. P.384-386. DOI: 10.1016/j.mencom.2018.07.014 WOS Scopus OpenAlex

Web of science:	WOS:000442709700014
Scopus:	2-s2.0-85051052552
OpenAlex:	W2886073162

БД	Цитирований
OpenAlex	18
Scopus	19
Web of science	19