4-Phenylspiro[2.2]pentane-1,1-dicarboxylate: synthesis and reactions with EtAlCl2 and 4,5-diazaspiro[2.4]hept-4-ene derivative

4-Phenylspiro[2.2]pentane-1,1-dicarboxylate: synthesis and reactions with EtAlCl2 and 4,5-diazaspiro[2.4]hept-4-ene derivative Научная публикация

Журнал

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Вых. Данные

Год: 2019, Том: 29, Номер: 4, Страницы: 417-418 Страниц : 2 DOI: 10.1016/j.mencom.2019.07.020

Авторы

Denisov Dmitry A. ¹ , Borisov Denis D. ¹ , Potapov Konstantin V. ¹ , Novikov Roman A. ¹ , Tomilov Yury V. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation

Cyclopropanation of 1-methylidene-2-phenylcyclopropane with dimethyl diazomalonate affords new dimethyl 4-phenyl-spiro[2.2]pentane-1,1-dicarboxylate. On contact with EtAlCl2, this compound undergoes opening of both cyclopropane rings to give dimethyl (2-chloromethyl-3-phenylallyl)malonate. Its EtAlCl2-assisted reaction with methyl 5′-methylspiro[cyclo-propane-1,3′-pyrazoline]-5′-carboxylate proceeds as the 1,3:1′,5′-addition to afford mainly 3-(2-chloroethyl)-1-cyclo-propylmethyl-1H-pyrazoline derivative.

Denisov D.A. , Borisov D.D. , Potapov K.V. , Novikov R.A. , Tomilov Y.V.
4-Phenylspiro[2.2]pentane-1,1-dicarboxylate: synthesis and reactions with EtAlCl2 and 4,5-diazaspiro[2.4]hept-4-ene derivative
Mendeleev Communications. 2019. V.29. N4. P.417-418. DOI: 10.1016/j.mencom.2019.07.020 WOS Scopus OpenAlex

≡ Web of science:	WOS:000484653500020
≡ Scopus:	2-s2.0-85070648318
≡ OpenAlex:	W2968634158