Synthesis of Phosphoryl Thioamides via Three‐Component Reaction of Phosphinic Chlorides with Amines and Sulfur

Synthesis of Phosphoryl Thioamides via Three‐Component Reaction of Phosphinic Chlorides with Amines and Sulfur Научная публикация

Журнал

Advanced Synthesis & Catalysis
ISSN: 1615-4169 , E-ISSN: 1615-4150

Вых. Данные

Год: 2019, Том: 361, Номер: 12, Страницы: 2904-2915 Страниц : 12 DOI: 10.1002/adsc.201900067

Авторы

Kozlov Mikhail ¹ , Kozlov Andrey ¹ , Komkov Alexander ¹ , Lyssenko Konstantin ^2,3 , Zavarzin Igor ¹ , Volkova Yulia ¹

Организации

1	N. D. Zelinsky Institute of Organic ChemistryRussian Academy of Sciences 47 Leninsky prosp. Moscow 119991 Russian Federation
2	A. N. Nesmeyanov Institute of Organoelement CompoundsRussian Academy of Sciences Vavilov str. 28, GSP-1 Moscow 119991 Russian Federation
3	Plekhanov Russian University of Economics Stremyanny per. 36 Moscow 117997 Russian Federation

A straightforward, practical, and atom-economical three-component synthesis of phosphoryl thioamides from phosphinic chlorides, elemental sulfur, and aliphatic amines has been developed. The scope and limitations of this transformation have been investigated. This protocol is distinguished by metal- and organic solvent-free conditions, and high tolerance to various functional groups; it can be adapted for scaled-up synthesis.

Kozlov M. , Kozlov A. , Komkov A. , Lyssenko K. , Zavarzin I. , Volkova Y.
Synthesis of Phosphoryl Thioamides via Three‐Component Reaction of Phosphinic Chlorides with Amines and Sulfur
Advanced Synthesis & Catalysis. 2019. V.361. N12. P.2904-2915. DOI: 10.1002/adsc.201900067 WOS Scopus OpenAlex

≡ Web of science:	WOS:000478036100014
≡ Scopus:	2-s2.0-85064486979
≡ OpenAlex:	W2923540480