4b,5,6,9-Tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin-7-one | Sciact

4b,5,6,9-Tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin-7-one Научная публикация

Журнал

Molbank
ISSN: 1422-8599

Вых. Данные

Год: 2019, Том: 2019, Номер: 2, Номер статьи : M1061, Страниц : DOI: 10.3390/m1061

Авторы

Boichenko Maksim A. ¹ , Babkin Igor Yu. ² , Kobylskoy Sergey G. ² , Chagarovskiy Alexey O. ^3,4 , Ivanova Olga A. ^1,4 , Trushkov Igor V. ^3,4

Организации

1	Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie gory 1-3, Moscow 119991, Russian
2	Laboratory of High Technologies, Ltd. Vernadskogo 86, Moscow 119571, Russian
3	Laboratory of Chemical Synthesis, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Samory Mashela 1, Moscow 117997, Russian
4	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russian

A simple approach to synthesize 4b,5,6,9-tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin- 7-one has been developed, based on a three-step transformation of 2-(2-bromophenyl)cyclopropane-1,1-diester. The key stage in this method is an intramolecular cross-coupling of 1-(2-bromobenzyl)-5-(2-bromophenyl)pyrrolidin-2-one under continuous flow conditions in an H-Сube-Pro using commercially available supported Pd catalysts.

Boichenko M.A. , Babkin I.Y. , Kobylskoy S.G. , Chagarovskiy A.O. , Ivanova O.A. , Trushkov I.V.
4b,5,6,9-Tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin-7-one
Molbank. 2019. V.2019. N2. M1061 . DOI: 10.3390/m1061 WOS Scopus OpenAlex

Web of science:	WOS:000477014200006
Scopus:	2-s2.0-85073271789
OpenAlex:	W2945143786

БД	Цитирований
OpenAlex	2
Scopus	1
Web of science	1