One-Pot Transformation of Aldehydes to Ketones via Minisci-Type Reaction of Imines

One-Pot Transformation of Aldehydes to Ketones via Minisci-Type Reaction of Imines Full article

Journal

Organic Letters
ISSN: 1523-7060 , E-ISSN: 1523-7052

Output data

Year: 2023, Volume: 25, Number: 48, Pages: 8751-8755 Pages count : 5 DOI: 10.1021/acs.orglett.3c03764

Authors

Rubanov Zakhar M. ^1,2 , Levin Vitalij V. ² , Dilman Alexander D. ²

Affiliations

1	Mendeleev University of Chemical Technology, Miusskaya Sq., 9, Moscow 125047, Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation

A method for the conversion of aldehydes to ketones via the preliminary formation of aldiminines is described. The imines are involved in acid promoted Minisci-type reaction with alkyl radicals generated from esters of N-hydroxylphthalimide under photoredox conditions. Aminyl radical cations formed after the addition of the iminium ions are believed to be key intermediates, which determine the reaction outcome.

Rubanov Z.M. , Levin V.V. , Dilman A.D.
One-Pot Transformation of Aldehydes to Ketones via Minisci-Type Reaction of Imines
Organic Letters. 2023. V.25. N48. P.8751-8755. DOI: 10.1021/acs.orglett.3c03764 WOS Scopus OpenAlex

Web of science:	WOS:001121846600001
Scopus:	2-s2.0-85179603801
OpenAlex:	W4389075182

DB	Citing
OpenAlex	5
Scopus	6
Web of science	3