Synthesis of unsaturated silyl nitronates via the silylation of conjugated nitroalkenes

Synthesis of unsaturated silyl nitronates via the silylation of conjugated nitroalkenes Full article

Journal

Tetrahedron Letters
ISSN: 0040-4039 , E-ISSN: 1873-3581

Output data

Year: 2018, Volume: 59, Number: 32, Pages: 3128-3131 Pages count : 4 DOI: 10.1016/j.tetlet.2018.07.011

Authors

Khotyantseva Elizaveta A. ^1,2 , Tabolin Andrey A. ¹ , Novikov Roman A. ^1,3 , Nelyubina Yulia V. ⁴ , Ioffe Sema L. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prosp. 47, Moscow 119991, Russia
2	Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie Gory 1, Moscow 119991, Russia
3	V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Str. 32, Moscow 119991, Russia
4	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov Str. 28, Moscow 119991, Russia

A new method for the synthesis of conjugated silyl nitronates from nitroalkenes is described. The procedure has wide substrate scope and is compatible with in situ generation of the substrates from 2-nitroalcohols or 2-chloro-nitroalkanes. A cascade transformation to give 3,4,5,6-tetrahydropyridine N-oxide derivatives was disclosed.

Khotyantseva E.A. , Tabolin A.A. , Novikov R.A. , Nelyubina Y.V. , Ioffe S.L.
Synthesis of unsaturated silyl nitronates via the silylation of conjugated nitroalkenes
Tetrahedron Letters. 2018. V.59. N32. P.3128-3131. DOI: 10.1016/j.tetlet.2018.07.011 WOS Scopus OpenAlex

≡ Web of science:	WOS:000440123000017
≡ Scopus:	2-s2.0-85049464449
≡ OpenAlex:	W2810401343