Oxidative C–O coupling as a new idea in the ‘click-like chemistry’: malonyl peroxides for the conjugation of two molecules

Oxidative C–O coupling as a new idea in the ‘click-like chemistry’: malonyl peroxides for the conjugation of two molecules Full article

Journal

Mendeleev Communications
ISSN: 1364-551X , E-ISSN: 0959-9436

Output data

Year: 2019, Volume: 29, Number: 2, Pages: 132-134 Pages count : 3 DOI: 10.1016/j.mencom.2019.03.003

Authors

Vil’ Vera A. ¹ , Gorlov Evgenii S. ^2,1 , Bityukov Oleg V. ¹ , Krylov Igor B. ¹ , Nikishin Gennady I. ¹ , Pivnitsky Kasimir K. ¹ , Terent’ev Alexander O. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russian Federation
2	D. I. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russian Federation

Malonyl peroxides were used for the one-pot construction of hybrid structures by conjugation of heterocycle (3H-pyrazol-3-one, isoxazol-5(2H)-one, pyrazolidine-3,5-dione, or barbituric acid) and amine or alcohol. The first stage represents oxidative C–O coupling with liberation of the carboxyl group which is functionalized at the second stage thus affording ‘clicklike’ products with malonic linker.

Vil’ V.A. , Gorlov E.S. , Bityukov O.V. , Krylov I.B. , Nikishin G.I. , Pivnitsky K.K. , Terent’ev A.O.
Oxidative C–O coupling as a new idea in the ‘click-like chemistry’: malonyl peroxides for the conjugation of two molecules
Mendeleev Communications. 2019. V.29. N2. P.132-134. DOI: 10.1016/j.mencom.2019.03.003 WOS Scopus OpenAlex

≡ Web of science:	WOS:000467509600003
≡ Scopus:	2-s2.0-85064316306
≡ OpenAlex:	W2940437142