Synthesis, S-alkylation, and fungicidal activity of 4-(benzylideneamino)thioglycolurils

Synthesis, S-alkylation, and fungicidal activity of 4-(benzylideneamino)thioglycolurils Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2018, Volume: 67, Number: 6, Pages: 1059-1064 Pages count : 6 DOI: 10.1007/s11172-018-2180-x

Authors

Gazieva G.A. ¹ , Nechaeva T.V. ² , Kostikova N.N. ¹ , Sigay N.V. ¹ , Serkov S.A. ¹ , Popkov S.V. ³

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
2	The State Scientific-Research Institute of Chemical Reagents and High Purity Chemical Substances, National Research Center “Kurchatov Institute”, Moscow, Russian Federation
3	D. I. Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation

A series of 1,3-disubstituted 4-benzylideneamino-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-ones (thioglycolurils) was synthesized via the reaction of 5,7-disubstituted 3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones with hydroxy-, alkoxy-, and fluorocontaining benzaldehyde derivatives. An alkylation of the obtained thioglycolurils with methyl iodide or 4-bromobenzyl bromide provided the corresponding 6-benzylideneamino-5-alkylsulfanyl-3,3a,6,6a-tetrahydroimidazo[4,5-d]imidazol-2(1H)-ones. The fungicidal activity of some synthesized compounds against pathogens causing diseases of agricultural crops was studied.

Gazieva G.A. , Nechaeva T.V. , Kostikova N.N. , Sigay N.V. , Serkov S.A. , Popkov S.V.
Synthesis, S-alkylation, and fungicidal activity of 4-(benzylideneamino)thioglycolurils
Russian Chemical Bulletin. 2018. V.67. N6. P.1059-1064. DOI: 10.1007/s11172-018-2180-x WOS Scopus OpenAlex

≡ Web of science:	WOS:000445942700019
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