Synthesis of 3-Fluoroindoles via Photoredox Catalysis

Synthesis of 3-Fluoroindoles via Photoredox Catalysis Full article

Journal

Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263

Output data

Year: 2017, Volume: 82, Number: 1, Pages: 745-753 Pages count : 9 DOI: 10.1021/acs.joc.6b02344

Authors

Panferova Liubov I. ¹ , Smirnov Vladimir O. ¹ , Levin Vitalij V. ¹ , Kokorekin Vladimir A. ^2,1 , Struchkova Marina I. ¹ , Dilman Alexander D. ¹

Affiliations

1	N.панD. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky prosp. 47, 119991 Moscow, Russian Federation
2	First I. M. Sechenov Moscow State Medical University, Trubetskaya st. 8-2, 119991 Moscow, Russian Federation

A method for the synthesis of 3-fluoroindoles from N-arylamines substituted with the CF2I group is described. The reaction is mediated by a ruthenium photocatalyst in the presence of a substoichiometric amount of triphenylphosphine upon irradiation with blue light. The starting N-arylamines are readily obtained by nucleophilic iododifluoromethylation of iminium ions.

Panferova L.I. , Smirnov V.O. , Levin V.V. , Kokorekin V.A. , Struchkova M.I. , Dilman A.D.
Synthesis of 3-Fluoroindoles via Photoredox Catalysis
Journal of Organic Chemistry. 2017. V.82. N1. P.745-753. DOI: 10.1021/acs.joc.6b02344 WOS Scopus OpenAlex

Web of science:	WOS:000391781900074
Scopus:	2-s2.0-85018479835
OpenAlex:	W2565238958

DB	Citing
OpenAlex	35
Scopus	34