Silicon Reagent with Functionalized Tetrafluoroethylene Fragments: Preparation and Coupling with Aldehydes Full article
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Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263 |
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| Output data | Year: 2016, Volume: 81, Number: 19, Pages: 9455-9460 Pages count : 6 DOI: 10.1021/acs.joc.6b01739 | ||
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Abstract:
A new fluorinated silicon reagent bearing a functionalized tetrafluoroethylene fragment was prepared from two CF2 building blocks: ethyl bromodifluoroacetate and (bromodifluoromethyl)trimethylsilane. The key C–C bond-forming step involves a difluorocarbene addition/cyclopropane rearrangement sequence. The silicon reagent was coupled with aldehydes and reactive azomethines in the presence of potassium fluoride.
Cite:
Fedorov O.V.
, Struchkova M.I.
, Dilman A.D.
Silicon Reagent with Functionalized Tetrafluoroethylene Fragments: Preparation and Coupling with Aldehydes
Journal of Organic Chemistry. 2016. V.81. N19. P.9455-9460. DOI: 10.1021/acs.joc.6b01739 WOS Scopus OpenAlex
Silicon Reagent with Functionalized Tetrafluoroethylene Fragments: Preparation and Coupling with Aldehydes
Journal of Organic Chemistry. 2016. V.81. N19. P.9455-9460. DOI: 10.1021/acs.joc.6b01739 WOS Scopus OpenAlex
Identifiers:
| Web of science: | WOS:000385054300079 |
| Scopus: | 2-s2.0-84990882856 |
| OpenAlex: | W2519510490 |