Silicon Reagent with Functionalized Tetrafluoroethylene Fragments: Preparation and Coupling with Aldehydes

Silicon Reagent with Functionalized Tetrafluoroethylene Fragments: Preparation and Coupling with Aldehydes Full article

Journal

Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263

Output data

Year: 2016, Volume: 81, Number: 19, Pages: 9455-9460 Pages count : 6 DOI: 10.1021/acs.joc.6b01739

Authors

Fedorov Oleg V. ¹ , Struchkova Marina I. ¹ , Dilman Alexander D. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russia

A new fluorinated silicon reagent bearing a functionalized tetrafluoroethylene fragment was prepared from two CF2 building blocks: ethyl bromodifluoroacetate and (bromodifluoromethyl)trimethylsilane. The key C–C bond-forming step involves a difluorocarbene addition/cyclopropane rearrangement sequence. The silicon reagent was coupled with aldehydes and reactive azomethines in the presence of potassium fluoride.

Fedorov O.V. , Struchkova M.I. , Dilman A.D.
Silicon Reagent with Functionalized Tetrafluoroethylene Fragments: Preparation and Coupling with Aldehydes
Journal of Organic Chemistry. 2016. V.81. N19. P.9455-9460. DOI: 10.1021/acs.joc.6b01739 WOS Scopus OpenAlex

Web of science:	WOS:000385054300079
Scopus:	2-s2.0-84990882856
OpenAlex:	W2519510490

DB	Citing
OpenAlex	21
Scopus	21
Web of science	19