Ring contraction of 1,2,4-triazine derivatives in the synthesis of imidazoles

Ring contraction of 1,2,4-triazine derivatives in the synthesis of imidazoles Обзор

Журнал

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Вых. Данные

Год: 2016, Том: 65, Номер: 9, Страницы: 2172-2182 Страниц : 11 DOI: 10.1007/s11172-016-1565-y

Авторы

Gazieva G.A. ¹ , Karpova T.B. ^1,2 , Nechaeva T.V. ^3,1 , Kravchenko A.N. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russian Federation
2	NPF Materia Medica Holding Ltd., Build. 1, 47 ul. Trifonovskaya, 129272 Moscow, Russian Federation
3	D. I. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya pl., 125047 Moscow, Russian Federation

The review systematizes the data on the reactions of 1,2,4-triazines proceeding with a triazine ring contraction to the imidazole one. Imidazole derivatives are obtained upon treatment of 1,2,4-triazines of different saturation degree with reducing agents, oxidants, acids, as well as with the agents initiating tandem reactions, the last step of which is a triazine ring contraction, for example, nitrosating and aminating agents, organometallic compounds and aromatic aldehydes.

Gazieva G.A. , Karpova T.B. , Nechaeva T.V. , Kravchenko A.N.
Ring contraction of 1,2,4-triazine derivatives in the synthesis of imidazoles
Russian Chemical Bulletin. 2016. V.65. N9. P.2172-2182. DOI: 10.1007/s11172-016-1565-y WOS Scopus OpenAlex

≡ Web of science:	WOS:000400400700007
≡ Scopus:	2-s2.0-85019040025
≡ OpenAlex:	W2609055118