Condensation of imidazole N-oxide with Meldrum’s acid and aldehydes: a new method for C2-functionalization of 2-unsubstituted imidazole N-oxides

Condensation of imidazole N-oxide with Meldrum’s acid and aldehydes: a new method for C2-functionalization of 2-unsubstituted imidazole N-oxides Full article

Journal

Tetrahedron Letters
ISSN: 0040-4039 , E-ISSN: 1873-3581

Output data

Year: 2016, Volume: 57, Number: 48, Pages: 5315-5316 Pages count : 2 DOI: 10.1016/j.tetlet.2016.10.061

Authors

Mityanov Vitaly S. ^1,2 , Kutasevich Anton V. ¹ , Krayushkin Michail M. ² , Lichitsky Boris V. ² , Dudinov Arkady A. ² , Komogortsev Andrey N. ² , Kuzmina Ludmila G. ³

Affiliations

1	Department of Fine Organic Synthesis and Chemistry of Dyes, D. Mendeleyev University of Chemical Technology of Russia, Miusskaya Sq., 9, Moscow 125047, Russian Federation
2	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Pr., 47, Moscow 119991, Russian Federation
3	N.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Science, Leninsky Pr., 31, Moscow 117907, Russian Federation

A novel condensation reaction between 1-benzyl-4,5-dimethylimidazole N-oxide, Meldrum’s acid, and various aldehydes is described. The reaction was applied to a broad scope of aldehydes, including aromatic and heteroaromatic aldehydes as well as aliphatic aldehydes and formaldehyde.

Mityanov V.S. , Kutasevich A.V. , Krayushkin M.M. , Lichitsky B.V. , Dudinov A.A. , Komogortsev A.N. , Kuzmina L.G.
Condensation of imidazole N-oxide with Meldrum’s acid and aldehydes: a new method for C2-functionalization of 2-unsubstituted imidazole N-oxides
Tetrahedron Letters. 2016. V.57. N48. P.5315-5316. DOI: 10.1016/j.tetlet.2016.10.061 WOS Scopus OpenAlex

Web of science:	WOS:000388781000006
Scopus:	2-s2.0-84994051840
OpenAlex:	W2538681495

DB	Citing
OpenAlex	9
Scopus	10
Web of science	10