Synthesis of functionalized organophosphorus derivatives of 2-oxopyrrolidine

Synthesis of functionalized organophosphorus derivatives of 2-oxopyrrolidine Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2024, Volume: 73, Number: 3, Pages: 634-643 Pages count : 10 DOI: 10.1007/s11172-024-4173-2

Authors

Bubnov Yu.N. ^1,3 , Prishchenko A.A. ² , Livantsov M.V. ² , Novikova O.P. ² , Livantsova L.I. ² , Baranin S.V. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
2	Chemical Department, M. V. Lomonosov Moscow State University, Build. 3 1 Leninskiye Gory, 119991, Moscow, Russian Federation
3	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Build. 1, 28 ul. Vavilova, 119991 Moscow, Russian Federation

A convenient synthesis of pyrrolidones substituted with functionalized phosphonous, phosphonic, and phosphinic acid residues has been developed. The radical addition of bis(trimethylsiloxy)phosphine to N-vinylpyrrolidone proceeds regioselectively to give 2-pyrrolidone-substituted ethylphosphonite, and its subsequent functionalization affords the target products. The resulting compounds are of interest as promising biologically active substances and water-soluble ligands.

Bubnov Y.N. , Prishchenko A.A. , Livantsov M.V. , Novikova O.P. , Livantsova L.I. , Baranin S.V.
Synthesis of functionalized organophosphorus derivatives of 2-oxopyrrolidine
Russian Chemical Bulletin. 2024. V.73. N3. P.634-643. DOI: 10.1007/s11172-024-4173-2 WOS Scopus OpenAlex

≡ Web of science:	WOS:001198897200005
≡ Scopus:	2-s2.0-85190102133
≡ OpenAlex:	W4394582910