Methyl (5-oxopyrazol-3-yl)acetate N,S-ketene acetal as a new building block for the construction of pyrazolo[4,3-c]pyridines

Methyl (5-oxopyrazol-3-yl)acetate N,S-ketene acetal as a new building block for the construction of pyrazolo[4,3-c]pyridines Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2016, Volume: 65, Number: 4, Pages: 1004-1007 Pages count : 4 DOI: 10.1007/s11172-016-1403-2

Authors

Prezent M.A. ¹ , Ruban S.V. ¹ , Baranin S.V. ¹ , Bubnov Yu.N. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

Methyl (5-oxopyrazol-3-yl)acetate is added to methylthiocyanate C≡N bond in the presence of Ni(OAc)2 giving a corresponding heterocyclic N,S-ketene acetal. The latter compound was used as a convenient synthon in the synthesis of new pyrazolo[4,3-c]pyridin-3-ones and pyrazolo[4,3-c]pyridine-3,6-diones.

Prezent M.A. , Ruban S.V. , Baranin S.V. , Bubnov Y.N.
Methyl (5-oxopyrazol-3-yl)acetate N,S-ketene acetal as a new building block for the construction of pyrazolo[4,3-c]pyridines
Russian Chemical Bulletin. 2016. V.65. N4. P.1004-1007. DOI: 10.1007/s11172-016-1403-2 WOS Scopus OpenAlex

≡ Web of science:	WOS:000392134600013
≡ Scopus:	2-s2.0-85008486113
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