A new approach to the synthesis of 3-amino- and 3-benzoylamino-5-aminoalkyl-1,2,4-triazoles

A new approach to the synthesis of 3-amino- and 3-benzoylamino-5-aminoalkyl-1,2,4-triazoles Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2015, Volume: 64, Number: 5, Pages: 1089-1092 Pages count : 4 DOI: 10.1007/s11172-015-0983-6

Authors

Prezent M.A. ¹ , Daeva E.D. ¹ , Baranin S.V. ¹ , Dorokhov V.A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

Nickel(II) acetylacetonate for the first time was shown to efficiently catalyze the addition of Boc-protected amino acid hydrazides to the nitrile group of benzoylcyanamide with the formation of the corresponding 3-benzoylamino-substituted 1,2,4-triazoles with the Boc-aminoalkyl group at position 5. A further modification of the latter led, depending on the conditions, to mono- or dihydrochlorides of 1,2,4-triazole-derived amines.

Prezent M.A. , Daeva E.D. , Baranin S.V. , Dorokhov V.A.
A new approach to the synthesis of 3-amino- and 3-benzoylamino-5-aminoalkyl-1,2,4-triazoles
Russian Chemical Bulletin. 2015. V.64. N5. P.1089-1092. DOI: 10.1007/s11172-015-0983-6 WOS Scopus OpenAlex

≡ Web of science:	WOS:000369426300016
≡ Scopus:	2-s2.0-84956661691
≡ OpenAlex:	W2337202171