Generation of Alkyl Radicals from Thiols via Zinc Thiolates: Application for the Synthesis of gem‐Difluorostyrenes

Generation of Alkyl Radicals from Thiols via Zinc Thiolates: Application for the Synthesis of gem‐Difluorostyrenes Full article

Journal

Advanced Synthesis & Catalysis
ISSN: 1615-4169 , E-ISSN: 1615-4150

Output data

Year: 2021, Volume: 363, Number: 11, Pages: 2888-2892 Pages count : 5 DOI: 10.1002/adsc.202100088

Authors

Supranovich Vyacheslav I. ¹ , Levin Vitalij V. ¹ , Kokorekin Vladimir A. ¹ , Dilman Alexander D. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry 119991 Moscow Leninsky prosp. 47 Russian Federation

Reaction of thiols with α-(trifluoromethyl)styrenes under photocatalytic conditions leading to desulfurative allylic fluorine substitution is described. The reaction is performed by treatment of thiols with benzyl zinc chloride to generate zinc thiolates followed by visible light induced desulfurization by means of triphenylphosphine. Radicals formed after the C−S bond cleavage react with the double bond affording gem-difluorostyrenes.

Supranovich V.I. , Levin V.V. , Kokorekin V.A. , Dilman A.D.
Generation of Alkyl Radicals from Thiols via Zinc Thiolates: Application for the Synthesis of gem‐Difluorostyrenes
Advanced Synthesis & Catalysis. 2021. V.363. N11. P.2888-2892. DOI: 10.1002/adsc.202100088 WOS Scopus OpenAlex

Web of science:	WOS:000635159800001
Scopus:	2-s2.0-85103662823
OpenAlex:	W3139210510

DB	Citing
OpenAlex	26
Web of science	24
Scopus	25