Synthesis of hexasaccharide fragment of lipoarabonomannan from Mycobacteria: advantages of the benzyl-free approach

Synthesis of hexasaccharide fragment of lipoarabonomannan from Mycobacteria: advantages of the benzyl-free approach Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2015, Volume: 64, Number: 5, Pages: 1149-1162 Pages count : 14 DOI: 10.1007/s11172-015-0992-5

Authors

Podvalnyy N.M. ¹ , Abronina P.I. ¹ , Fedina K.G. ¹ , Kondakov N.N. ¹ , Zinin A.I. ¹ , Chizhov A.O. ¹ , Torgov V.I. ¹ , Kachala V.V. ¹ , Kononov L.O. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

Spacered branched hexaarabinofuranoside, which corresponds to the terminal fragment of mycobacterial lipoarabinomannan and arabinogalactan, was synthesized via three different routes. Synthetic scheme which involved only acyl and silyl protective groups (benzyl-free approach) allows one to reduce the number of deprotection steps, enhance the overall yield, and keep the azido group until the end of the synthesis.

Podvalnyy N.M. , Abronina P.I. , Fedina K.G. , Kondakov N.N. , Zinin A.I. , Chizhov A.O. , Torgov V.I. , Kachala V.V. , Kononov L.O.
Synthesis of hexasaccharide fragment of lipoarabonomannan from Mycobacteria: advantages of the benzyl-free approach
Russian Chemical Bulletin. 2015. V.64. N5. P.1149-1162. DOI: 10.1007/s11172-015-0992-5 WOS Scopus OpenAlex

Web of science:	WOS:000369426300025
Scopus:	2-s2.0-84956601349
OpenAlex:	W2394916096

DB	Citing
OpenAlex	25
Scopus	27
Web of science	24