Nitropyrazoles 23. Synthesis of substituted N-amino-3-nitro-5-R-pyrazoles

Nitropyrazoles 23. Synthesis of substituted N-amino-3-nitro-5-R-pyrazoles Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2014, Volume: 63, Number: 2, Pages: 435-442 Pages count : 8 DOI: 10.1007/s11172-014-0450-9

Authors

Kormanov A.V. ¹ , Shkineva T.K. ¹ , Vatsadze I.A. ¹ , Shevelev S.A. ¹ , Dalinger I.L. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

The study is devoted to nucleophilic substitution of nitro groups in 1-amino-3,5-dinitropyrazole (1) and its amino group derived analogs. Compound 1 upon treatment with S-nucleophiles undergoes regioselective substitution of the nitro group at position 5. Azomethine 5 obtained by the condensation of 1 with benzaldehyde gives the nucleophilic substitution reaction with S-, O-and N-nucleophiles also with involvement of the nitro group at position 5. The synthesized 5-R-substituted azomethines 7–9 upon treatment with hydrazine hydrate form N-amino-5-R-3-nitropyrazoles and benzaldazine.

Kormanov A.V. , Shkineva T.K. , Vatsadze I.A. , Shevelev S.A. , Dalinger I.L.
Nitropyrazoles 23. Synthesis of substituted N-amino-3-nitro-5-R-pyrazoles
Russian Chemical Bulletin. 2014. V.63. N2. P.435-442. DOI: 10.1007/s11172-014-0450-9 WOS Scopus OpenAlex

≡ Web of science:	WOS:000343607900018
≡ Scopus:	2-s2.0-84910134638
≡ OpenAlex:	W2136575657