Convenient Synthesis and Purification ofN-Trifluoroacetylated Neuraminic Acid Tetraol: A Key Precursor for the Synthesis of New Sialyl Donors Containing LabileO-Acyl Protecting Groups Научная публикация
| Журнал |
Journal of Carbohydrate Chemistry
ISSN: 0732-8303 , E-ISSN: 1532-2327 |
||
|---|---|---|---|
| Вых. Данные | Год: 2014, Том: 33, Номер: 5, Страницы: 213-224 Страниц : 12 DOI: 10.1080/07328303.2014.913058 | ||
| Авторы |
|
||
| Организации |
|
Реферат:
A convenient synthesis and separation of α- and β-anomers of methyl (phenyl 3,5-dideoxy-2-thio-5-trifluoroacetamido-D-glycero-D-galacto-nonulopyranosid)onate (6a and 6b) on a multigram scale was developed. Both α- and β-isomers of 6 were obtained as crystals suitable for safe storage. The β-isomer forms a crystalline solvate with methanol. Fully O-trichloroacetylated and O-trifluoroacetylated N-trifluoroacetyl thiosialosides were synthesized in an efficient manner from the β-tetraol 6b.
Библиографическая ссылка:
Podvalnyy N.M.
, Zinin A.I.
, Malysheva N.N.
, Kunetskiy R.A.
, Kononov L.O.
Convenient Synthesis and Purification ofN-Trifluoroacetylated Neuraminic Acid Tetraol: A Key Precursor for the Synthesis of New Sialyl Donors Containing LabileO-Acyl Protecting Groups
Journal of Carbohydrate Chemistry. 2014. V.33. N5. P.213-224. DOI: 10.1080/07328303.2014.913058 WOS Scopus OpenAlex
Convenient Synthesis and Purification ofN-Trifluoroacetylated Neuraminic Acid Tetraol: A Key Precursor for the Synthesis of New Sialyl Donors Containing LabileO-Acyl Protecting Groups
Journal of Carbohydrate Chemistry. 2014. V.33. N5. P.213-224. DOI: 10.1080/07328303.2014.913058 WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:000337946800001 |
| Scopus: | 2-s2.0-84903588160 |
| OpenAlex: | W2003980018 |