Synthesis of 4-Acyl-3-Aminofurazans from 3,4-Diacylfuroxans

Synthesis of 4-Acyl-3-Aminofurazans from 3,4-Diacylfuroxans Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 1573-8353 , E-ISSN: 0009-3122

Output data

Year: 2014, Volume: 50, Number: 8, Pages: 1154-1165 Pages count : 12 DOI: 10.1007/s10593-014-1576-2

Authors

Sheremetev A.B. ¹ , Zabusov S.G. ¹ , Tukhbatshin T.R. ¹ , Palysaeva N.V. ¹ , Suponitsky K.Yu. ²

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
2	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russia

It was shown that 3,4-diaroylfuroxans are transformed into the corresponding 3-amino-4-aroyl-furazans by heating in aqueous ammonia. The developed one-pot methodology for the synthesis of 3-amino-4-aroylfurazans involved the interaction of the corresponding acetophenones with nitric acid followed by treatment of the in situ formed furoxans with ammonia at elevated temperature. The structures of the obtained furazans were confirmed by IR, as well as by 1H and 13C NMR spectroscopy, and X-ray structural analysis was performed for 3-amino-4-(4-methoxybenzoyl)furazan.

Sheremetev A.B. , Zabusov S.G. , Tukhbatshin T.R. , Palysaeva N.V. , Suponitsky K.Y.
Synthesis of 4-Acyl-3-Aminofurazans from 3,4-Diacylfuroxans
Chemistry of Heterocyclic Compounds. 2014. V.50. N8. P.1154-1165. DOI: 10.1007/s10593-014-1576-2 WOS Scopus OpenAlex

≡ Web of science:	WOS:000344093400011
≡ Scopus:	2-s2.0-84922079870
≡ OpenAlex:	W2159155094