Recent advances in the synthesis of fungal antigenic oligosaccharides

Recent advances in the synthesis of fungal antigenic oligosaccharides Full article

Journal

Pure and Applied Chemistry
ISSN: 0033-4545 , E-ISSN: 1365-3075

Output data

Year: 2017, Volume: 89, Number: 7, Pages: 885-898 Pages count : 14 DOI: 10.1515/pac-2016-1011

Authors

Krylov Vadim B. ¹ , Paulovičová Lucia ² , Paulovičová Ema ² , Tsvetkov Yury E. ¹ , Nifantiev Nikolay E. ¹

Affiliations

1	Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia
2	Department of Immunochemistry of Glycoconjugates, Center for Glycomics , Institute of Chemistry, Slovakia Slovak Academy of Sciences , Dubravská cesta 9, 84538 Bratislava , Slovakia

The driving force for the constant improvement and development of new synthetic methodologies in carbohydrate chemistry is a growing demand for biologically important oligosaccharide ligands and neoglycoconjugates thereof for numerous biochemical investigations such as cell-to-pathogen interactions, immune response, cell adhesion, etc. Here we report our syntheses of the spacer-armed antigenic oligosaccharides related to three groups of the polysaccharides of the fungal cell-wall including α- and β-mannan, α- and β-glucan and galactomannan chains, which include new rationally designed synthetic blocks, efficient solutions for the stereoselective construction of glycoside bonds, and novel strategy for preparation of furanoside-containing oligosaccharides based on recently discovered pyranoside-into-furanoside (PIF) rearrangement.

Krylov V.B. , Paulovičová L. , Paulovičová E. , Tsvetkov Y.E. , Nifantiev N.E.
Recent advances in the synthesis of fungal antigenic oligosaccharides
Pure and Applied Chemistry. 2017. V.89. N7. P.885-898. DOI: 10.1515/pac-2016-1011 WOS Scopus OpenAlex

≡ Web of science:	WOS:000407335400004
≡ Scopus:	2-s2.0-85023164057
≡ OpenAlex:	W2562140190