Facile Synthesis of Natural Alkoxynaphthalene Analogues from Plant Alkoxybenzenes

Facile Synthesis of Natural Alkoxynaphthalene Analogues from Plant Alkoxybenzenes Full article

Journal

Journal of Natural Products
ISSN: 0163-3864 , E-ISSN: 1520-6025

Output data

Year: 2016, Volume: 79, Number: 4, Pages: 923-928 Pages count : 6 DOI: 10.1021/acs.jnatprod.5b01007

Authors

Tsyganov Dmitry V. ¹ , Krayushkin Mikhail M. ¹ , Konyushkin Leonid D. ¹ , Strelenko Yuri A. ¹ , Semenova Marina N. ^2,3 , Semenov Victor V. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, RAS, Leninsky Prospect, 47, 119991, Moscow, Russian Federation
2	Chemical Block Ltd., 3 Kyriacou Matsi, 3723, Limassol, Cyprus
3	Institute of Developmental Biology, RAS, Vavilov Street, 26, 119334, Moscow, Russian Federation

Analogues of the bioactive natural alkoxynaphthalene pycnanthulignene D were synthesized by an efficient method. The starting plant allylalkoxybenzenes (1) are easily available from the plant essential oils of sassafras, dill, and parsley. The target 1-arylalkoxynaphthalenes (5) exhibited antiproliferative activity in a phenotypic sea urchin embryo assay.

Tsyganov D.V. , Krayushkin M.M. , Konyushkin L.D. , Strelenko Y.A. , Semenova M.N. , Semenov V.V.
Facile Synthesis of Natural Alkoxynaphthalene Analogues from Plant Alkoxybenzenes
Journal of Natural Products. 2016. V.79. N4. P.923-928. DOI: 10.1021/acs.jnatprod.5b01007 WOS Scopus OpenAlex

Web of science:	WOS:000374915800033
Scopus:	2-s2.0-84967317320
OpenAlex:	W2281096563

DB	Citing
OpenAlex	6
Scopus	7
Web of science	7