A comparison of electrospray tandem mass spectra of some sialic acid derivatives: Ion trap and high resolution QqToF mass spectrometers

A comparison of electrospray tandem mass spectra of some sialic acid derivatives: Ion trap and high resolution QqToF mass spectrometers Full article

Journal

Journal of Analytical Chemistry
ISSN: 1608-3199 , E-ISSN: 1061-9348

Output data

Year: 2016, Volume: 71, Number: 14, Pages: 1392-1396 Pages count : 5 DOI: 10.1134/s1061934816140045

Authors

Chizhov A.O. ¹ , Shpirt A.M. ¹ , Savel’eva N.Y. ^1,2 , Kononov L.O. ¹

Affiliations

1	Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991 Russia
2	Higher Chemical College, Russian Academy of Sciences, Moscow, 125047 Russia

Using O-acetyl-N-acyl derivatives of O-methyl sialoside methyl esters, it was shown that an ion trap and a hybrid analyzer (linear quadrupole–time-of-flight analyzer, reflectron) give comparable, though not identical secondary mass spectra for the [M + Na]+ and [M + K]+ ions. A parallel use of an ion trap and a hybrid QqToF instrument gives information about the fragmentation pathways of ions of sialic acid derivatives under collisional activation. In this case, the sequence of fragmentation may be established using an ion trap, whereas a QqToF instrument offers a possibility of revealing the elemental composition of fragment ions quickly and unequivocally.

Chizhov A.O. , Shpirt A.M. , Savel’eva N.Y. , Kononov L.O.
A comparison of electrospray tandem mass spectra of some sialic acid derivatives: Ion trap and high resolution QqToF mass spectrometers
Journal of Analytical Chemistry. 2016. V.71. N14. P.1392-1396. DOI: 10.1134/s1061934816140045 WOS Scopus OpenAlex

Web of science:	WOS:000394346500015
Scopus:	2-s2.0-85012982840
OpenAlex:	W2588995105

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OpenAlex	1
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