Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease

Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease Обзор

Журнал

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Вых. Данные

Год: 2015, Том: 64, Номер: 6, Страницы: 1240-1248 Страниц : 9 DOI: 10.1007/s11172-015-1007-2

Авторы

Boyko Ya.D. ^1,2 , Sukhorukov A.Yu. ¹ , Ioffe S.L. ¹ , Tartakovsky V.A. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation
2	Higher Chemical College of the Russian Academy of Sciences, 9 Miusskaya pl., 125047 Moscow, Russian Federation.

The review summarizes the known approaches to diastereo- and enantioselective synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)hexahydro-3H-pyrrolizin-3-one (Pyrromilast), a highly active inhibitor of subtype 4B phosphodiesterase and a promising agent for treatment of chronic obstructive pulmonary disease.

Boyko Y.D. , Sukhorukov A.Y. , Ioffe S.L. , Tartakovsky V.A.
Advances in the synthesis of 7-(3-cyclopentyloxy-4-methoxyphenyl)-hexahydro-3H-pyrrolizin-3-one (Pyrromilast)–a promising agent for treatment of chronic obstructive pulmonary disease
Russian Chemical Bulletin. 2015. V.64. N6. P.1240-1248. DOI: 10.1007/s11172-015-1007-2 WOS Scopus OpenAlex

Web of science:	WOS:000371313900004
Scopus:	2-s2.0-84959322794
OpenAlex:	W2339690412

БД	Цитирований
OpenAlex	5
Scopus	5
Web of science	4