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Free-radical and electrophilic functionalization of pyrazol-3-ones with C–O or C–N bond formation (microreview) Review

Journal Chemistry of Heterocyclic Compounds
ISSN: 1573-8353 , E-ISSN: 0009-3122
Output data Year: 2021, Volume: 57, Number: 2, Pages: 134-136 Pages count : 3 DOI: 10.1007/s10593-021-02885-8
Authors Lopat’eva Elena R. 1 , Krylov Igor B. 1
Affiliations
1 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow, 119991, Russia

Abstract: Pyrazol-3-ones are known as a class of anti-inflammatory drugs and popular heterocycles in search for new bioactive substances. The electrophilic or freeradical functionalization of C-4 position of pyrazolin-3-ones with the formation of C–C, C–S, C–Hal, C–N, and C–O bonds has been extensively developed in the last decade. Among these methods, the C–O or C–N bond forming reactions are studied less. This microreview covers selected examples of such reactions published in the last 10 years.
Cite: Lopat’eva E.R. , Krylov I.B.
Free-radical and electrophilic functionalization of pyrazol-3-ones with C–O or C–N bond formation (microreview)
Chemistry of Heterocyclic Compounds. 2021. V.57. N2. P.134-136. DOI: 10.1007/s10593-021-02885-8 WOS Scopus OpenAlex
Identifiers:
≡ Web of science: WOS:000624405400008
≡ Scopus: 2-s2.0-85102053911
≡ OpenAlex: W3134255890
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