Synthesis of functionalized imidazo[4,5-e]thiazolo[3,2-b]triazines by condensation of imidazo[4,5-e]triazinethiones with DMAD or DEAD and rearrangement to imidazo[4,5-e]thiazolo[2,3-c]triazines

Synthesis of functionalized imidazo[4,5-e]thiazolo[3,2-b]triazines by condensation of imidazo[4,5-e]triazinethiones with DMAD or DEAD and rearrangement to imidazo[4,5-e]thiazolo[2,3-c]triazines Full article

Journal

Beilstein Journal of Organic Chemistry
ISSN: 2195-951X , E-ISSN: 1860-5397

Output data

Year: 2021, Volume: 17, Pages: 1141-1148 Pages count : 8 DOI: 10.3762/bjoc.17.87

Authors

Izmest’ev Alexei N ^1,2 , Vinogradov Dmitry B ¹ , Kolotyrkina Natalya G ¹ , Kravchenko Angelina N ^1,3 , Gazieva Galina A ¹

Affiliations

1	Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prosp., 47, Moscow 119991, Russian Federation,
2	National University of Science and Technology (MISiS), 4 Leninsky prosp., Moscow 119049, Russian Federation and
3	Plekhanov Russian University of Economics, 36 Stremyanny Lane, Moscow 117997, Russian Federation

Two series of functionalized imidazothiazolotriazine derivatives were synthesized via the condensation of imidazo[4,5-e]-1,2,4-triazine-3-thiones with acetylenedicarboxylic acid dimethyl and diethyl esters (DMAD and DEAD) and subsequent base-catalyzed rearrangement of the obtained imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazines into regioisomeric imidazo[4,5-e]thiazolo[2,3-c]-1,2,4-triazine derivatives.

Izmest’ev A.N. , Vinogradov D.B. , Kolotyrkina N.G. , Kravchenko A.N. , Gazieva G.A.
Synthesis of functionalized imidazo[4,5-e]thiazolo[3,2-b]triazines by condensation of imidazo[4,5-e]triazinethiones with DMAD or DEAD and rearrangement to imidazo[4,5-e]thiazolo[2,3-c]triazines
Beilstein Journal of Organic Chemistry. 2021. V.17. P.1141-1148. DOI: 10.3762/bjoc.17.87 WOS Scopus OpenAlex

≡ Web of science:	WOS:000651414700001
≡ Scopus:	2-s2.0-85106371088
≡ OpenAlex:	W3163113771