New Method for the Synthesis and Reactivity of (5‐R‐1,3,4‐Oxadiazol‐2‐yl)furoxans

New Method for the Synthesis and Reactivity of (5‐R‐1,3,4‐Oxadiazol‐2‐yl)furoxans Full article

Journal

Journal of Heterocyclic Chemistry
ISSN: 0022-152X , E-ISSN: 1943-5193

Output data

Year: 2016, Volume: 53, Number: 1, Pages: 102-108 Pages count : 7 DOI: 10.1002/jhet.1940

Authors

Fershtat Leonid L. ¹ , Kulikov Alexander S. ¹ , Ananyev Ivan V. ² , Struchkova Marina I. ¹ , Makhova Nina N. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky pr., 119991 Moscow, Russian Federation
2	A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28, Vavilova st, 119991 Moscow, Russian Federation

A new, simple and general one-pot method for the preparation of (5-R-1,3,4-oxadiazol-2-yl)furoxans has been developed on the basis of the interaction between accessible 3-methylfuroxan-4-carboxylic acid hydrazide and aliphatic, aromatic and heterocyclic carboxylic acids or their chlorides in the presence of POCl3. The synthesis and study of (5-R-1,3,4-oxadiazol-2-yl)furoxans reactivity resulted in new polyheterocyclic ensembles incorporating furoxan, 1,3,4-oxadiazole, pyrrole, triazole, furan, thiophene, pyrimidine, and other heterocycles in different combinations.

Fershtat L.L. , Kulikov A.S. , Ananyev I.V. , Struchkova M.I. , Makhova N.N.
New Method for the Synthesis and Reactivity of (5‐R‐1,3,4‐Oxadiazol‐2‐yl)furoxans
Journal of Heterocyclic Chemistry. 2016. V.53. N1. P.102-108. DOI: 10.1002/jhet.1940 WOS Scopus OpenAlex

≡ Web of science:	WOS:000369003300013
≡ Scopus:	2-s2.0-84956709611
≡ OpenAlex:	W2527416700