Five-Membered Hetarene N-Oxides: Recent Advances in Synthesis and Reactivity

Five-Membered Hetarene N-Oxides: Recent Advances in Synthesis and Reactivity Review

Journal

Synthesis-Stuttgart
ISSN: 1437-210X , E-ISSN: 0039-7881

Output data

Year: 2021, Volume: 53, Number: 20, Pages: 3673-3682 Pages count : 10 DOI: 10.1055/a-1529-7678

Authors

Fershtat Leonid L. ^1,2 , Teslenko Fedor E. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
2	National Research University Higher School of Economics

Five-membered heterocyclic N-oxides attract special attention due to their significant potential applications in medicinal chemistry and advanced materials science. In this regard, novel methods for their synthesis and functionalization are in constant demand. In this short review, recent state-of-the-art achievements in the chemistry of isoxazoline N-oxides, 1,2,3-triazole 1-oxides and 1,2,5-oxadiazole 2-oxides are summarized. The main routes involving transition-metal-catalyzed and metal-free functionalization protocols along with mechanistic considerations are outlined. The transformations of these hetarene N-oxide rings as precursors to other nitrogen heterocyclic systems are also presented.

Fershtat L.L. , Teslenko F.E.
Five-Membered Hetarene N-Oxides: Recent Advances in Synthesis and Reactivity
Synthesis-Stuttgart. 2021. V.53. N20. P.3673-3682. DOI: 10.1055/a-1529-7678 WOS Scopus OpenAlex

Web of science:	WOS:000681423000001
Scopus:	2-s2.0-85112366168
OpenAlex:	W3170633625

DB	Citing
OpenAlex	29
Web of science	27
Scopus	29