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General approach to spiroacenaphthylene pentacyclic systems: direct multicomponent assembling of acenaphthenequinone and cyclic carbonyl compounds with two molecules of malononitrile Научная публикация

Журнал Tetrahedron
ISSN: 0040-4020 , E-ISSN: 1464-5416
Вых. Данные Год: 2013, Том: 69, Номер: 34, Страницы: 7125-7130 Страниц : 6 DOI: 10.1016/j.tet.2013.06.015
Авторы Elinson Michail N. 1 , Ilovaisky Alexey I. 1 , Merkulova Valentina M. 1 , Barba Fructuoso 2 , Batanero Belen 2
Организации
1 N. D. Zelinsky Institute of Organic Chemistry, Leninsky Prospect 47, 119991 Moscow, Russia
2 Department of Organic Chemistry, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain

Реферат: A new type of catalytic cascade reaction was found: the direct multicomponent transformation of acenaphthenequinone, cyclic ketones, and two molecules of malononitrile into spiroacenaphthylene pentacyclic systems. The fast (5 min) reaction of acenaphthenequinone, cyclic ketones, and 2 equiv of malononitrile at ambient temperature results in the formation of pentacyclic and pentaheterocyclic spiroacenaphthylene frameworks in 70–95% yields. Thus, a new simple fast and efficient ‘one-pot’ method to synthesize substituted spiroacenaphthylene frameworks was found directly from simple starting compounds. The application of this convenient multicomponent method is also beneficial from the viewpoint of diversity-oriented large-scale processes.
Библиографическая ссылка: Elinson M.N. , Ilovaisky A.I. , Merkulova V.M. , Barba F. , Batanero B.
General approach to spiroacenaphthylene pentacyclic systems: direct multicomponent assembling of acenaphthenequinone and cyclic carbonyl compounds with two molecules of malononitrile
Tetrahedron. 2013. V.69. N34. P.7125-7130. DOI: 10.1016/j.tet.2013.06.015 WOS Scopus OpenAlex
Идентификаторы БД:
Web of science: WOS:000322098000026
Scopus: 2-s2.0-84880134413
OpenAlex: W2951210677
Цитирование в БД:
БД Цитирований
OpenAlex 49
Scopus 45
Web of science 44
Альметрики: