3-R-4-Nitro-6,7-furoxanobenzo[d]isoxazoles – a new type of condensed nitroarenes capable of Diels–Alder reaction

3-R-4-Nitro-6,7-furoxanobenzo[d]isoxazoles – a new type of condensed nitroarenes capable of Diels–Alder reaction Full article

Journal

Chemistry of Heterocyclic Compounds
ISSN: 1573-8353 , E-ISSN: 0009-3122

Output data

Year: 2015, Volume: 51, Number: 5, Pages: 496-499 Pages count : 4 DOI: 10.1007/s10593-015-1726-1

Authors

Bastrakov Maxim A. ¹ , Starosotnikov Alexey M. ¹ , Kachala Vadim V. ¹ , Dalinger Igor L. ¹ , Shevelev Svyatoslav A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

Pericyclic [4+2] cycloaddition (Diels–Alder reaction) of nitrofuroxanobenzo[d]isoxazoles, capable of acting both as dienophiles (at the C=CNO2 bond) or heterodienes (at the C=C–N(O)=O fragment) was used to synthesize a new type of condensed polycyclic systems. The obtained compounds combining in one molecule two pharmacophore moieties, furoxan (nitric oxide donor) and substituted isoxazole, may be considered as a potential basis for the design of compounds with dual biological activity.

Bastrakov M.A. , Starosotnikov A.M. , Kachala V.V. , Dalinger I.L. , Shevelev S.A.
3-R-4-Nitro-6,7-furoxanobenzo[d]isoxazoles – a new type of condensed nitroarenes capable of Diels–Alder reaction
Chemistry of Heterocyclic Compounds. 2015. V.51. N5. P.496-499. DOI: 10.1007/s10593-015-1726-1 WOS Scopus OpenAlex

Web of science:	WOS:000358138200013
Scopus:	2-s2.0-84943244076
OpenAlex:	W2099060933

DB	Citing
OpenAlex	23
Scopus	27
Web of science	24