Green Approach to the Design of Functionalized Medicinally Privileged 4‐Aryl‐1,4‐dihydropyrano[2,3‐c]‐pyrazole‐5‐carbonitrile Scaffold

Green Approach to the Design of Functionalized Medicinally Privileged 4‐Aryl‐1,4‐dihydropyrano[2,3‐c]‐pyrazole‐5‐carbonitrile Scaffold Full article

Journal

Journal of Heterocyclic Chemistry
ISSN: 0022-152X , E-ISSN: 1943-5193

Output data

Year: 2014, Volume: 51, Number: 2, Pages: 523-526 Pages count : 4 DOI: 10.1002/jhet.1737

Authors

Ilovaisky Alexey I. ¹ , Medvedev Michael G. ¹ , Merkulova Valentina M. ¹ , Elinson Michail N. ¹ , Nikishin Gennady I. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Leninsky prospect 47, 119991 Moscow, Russia

“On water” multicomponent condensation of aromatic aldehydes, malononitrile, and 3-methyl-2-pyrazoline-5-one in the presence of sodium hydroxide as catalyst leads to 6-amino-3-methyl-4-aryl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles in 85–98% yields.

Ilovaisky A.I. , Medvedev M.G. , Merkulova V.M. , Elinson M.N. , Nikishin G.I.
Green Approach to the Design of Functionalized Medicinally Privileged 4‐Aryl‐1,4‐dihydropyrano[2,3‐c]‐pyrazole‐5‐carbonitrile Scaffold
Journal of Heterocyclic Chemistry. 2014. V.51. N2. P.523-526. DOI: 10.1002/jhet.1737 WOS Scopus OpenAlex

Web of science:	WOS:000333382000034
Scopus:	2-s2.0-84897425276
OpenAlex:	W2296217741

DB	Citing
OpenAlex	17
Scopus	16
Web of science	16