Boron Trifluoride as an Efficient Catalyst for the Selective Synthesis of Tricyclic Monoperoxides from β,δ-Triketones and H2O2

Boron Trifluoride as an Efficient Catalyst for the Selective Synthesis of Tricyclic Monoperoxides from β,δ-Triketones and H2O2 Full article

Journal

Synthesis-Stuttgart
ISSN: 1437-210X , E-ISSN: 0039-7881

Output data

Year: 2013, Volume: 45, Number: 02, Pages: 246-250 Pages count : 5 DOI: 10.1055/s-0032-1317895

Authors

Terent’ev Alexander ¹ , Yaremenko Ivan ¹ , Vil’ Vera ¹ , Dembitsky Valery ² , Nikishin Gennady ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences
2	Institute for Drug Research, P. O. Box 12065, Hebrew University

Boron trifluoride was found to serve as an efficient catalyst for the reaction of β,δ-triketones with H2O2 producing tricyclic monoperoxides in yields from 48–93%. BF3 acts simultaneously as a catalyst and co-solvent. The synthesis can be scaled up to tens of grams. The resulting peroxides can be easily isolated from the reaction mixture by column chromatography.

Terent’ev A. , Yaremenko I. , Vil’ V. , Dembitsky V. , Nikishin G.
Boron Trifluoride as an Efficient Catalyst for the Selective Synthesis of Tricyclic Monoperoxides from β,δ-Triketones and H2O2
Synthesis-Stuttgart. 2013. V.45. N02. P.246-250. DOI: 10.1055/s-0032-1317895 WOS Scopus OpenAlex

≡ Web of science:	WOS:000313362800015
≡ Scopus:	2-s2.0-84872187168
≡ OpenAlex:	W2316861229