Synthesis and Antifungal Activity of Arylthiocyanates

Synthesis and Antifungal Activity of Arylthiocyanates Full article

Journal

Pharmaceutical Chemistry Journal
ISSN: 0091-150X , E-ISSN: 1573-9031

Output data

Year: 2013, Volume: 47, Number: 8, Pages: 422-425 Pages count : 4 DOI: 10.1007/s11094-013-0973-7

Authors

Kokorekin V.A. ^1,2 , Terent’ev A.O. ¹ , Ramenskaya G.V. ² , Grammatikova N.É. ^2,3 , Rodionova G.M. ² , Ilovaiskii A.I. ¹

Affiliations

1	N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
2	First I. M. Sechenov Moscow State Medical University, Moscow, Russia
3	State Scientific Center for Antibiotics, Moscow, Russia

A new method for the synthesis of arylthiocyanates from derivatives of aniline, pyrrole, and indole is described. Products had antimicrobial activity. Dithiocyanates N-methylpyrrole and N-phenylpyrrole were active against Candida albicans, Candida tropicalis, Candida krusei, and Aspergillus niger with activity levels comparable to those of fluconazole and amphotericin.

Kokorekin V.A. , Terent’ev A.O. , Ramenskaya G.V. , Grammatikova N.É. , Rodionova G.M. , Ilovaiskii A.I.
Synthesis and Antifungal Activity of Arylthiocyanates
Pharmaceutical Chemistry Journal. 2013. V.47. N8. P.422-425. DOI: 10.1007/s11094-013-0973-7 WOS Scopus OpenAlex

Web of science:	WOS:000328631900006
Scopus:	2-s2.0-84891482411
OpenAlex:	W2050234111

DB	Citing
OpenAlex	69
Scopus	68
Web of science	71