Nitropyrazoles 22. On reactivity of 3,5-dinitro-4-(phenylsulfonyl)pyrazole and its N-methyl derivative

Nitropyrazoles 22. On reactivity of 3,5-dinitro-4-(phenylsulfonyl)pyrazole and its N-methyl derivative Full article

Journal

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Output data

Year: 2012, Volume: 61, Number: 2, Pages: 469-471 Pages count : 3 DOI: 10.1007/s11172-012-0067-9

Authors

Vatsadze I.A. ¹ , Dalinger I.L. ¹ , Shkineva T.K. ¹ , Popova G.P. ¹ , Shevelev S.A. ¹

Affiliations

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

3,5-Dinitro-4-(phenylsulfonyl)pyrazole (5) obtained by oxidation of 3,5-dinitro-4-(phenylthio)pyrazole with 30% H2O2 in AcOH was involved into nucleophilic substitution reaction with thiophenol, which proceeded with substitution of the phenylsulfonyl group at position 4. N-Methyl-3,5-dinitro-4-(phenylsulfonyl)pyrazole obtained by methylation of 5 with dimethyl sulfate was involved into nucleophilic substitution reaction with thiophenol, p-bromophenol, and morpholine with the regioselective substitution of the nitro group at position 5 to form 5-R-3-nitro-4-(phenylsulfonyl)pyrazoles.

Vatsadze I.A. , Dalinger I.L. , Shkineva T.K. , Popova G.P. , Shevelev S.A.
Nitropyrazoles 22. On reactivity of 3,5-dinitro-4-(phenylsulfonyl)pyrazole and its N-methyl derivative
Russian Chemical Bulletin. 2012. V.61. N2. P.469-471. DOI: 10.1007/s11172-012-0067-9 WOS Scopus OpenAlex

≡ Web of science:	WOS:000312068000036
≡ Scopus:	2-s2.0-84877041737
≡ OpenAlex:	W1982678937