Three-Component Electrochemical Aminoselenation of 1,3-Dienes

Three-Component Electrochemical Aminoselenation of 1,3-Dienes Full article

Journal

Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263

Output data

Year: 2023, Volume: 88, Number: 9, Pages: 5760-5771 Pages count : 12 DOI: 10.1021/acs.joc.3c00214

Authors

Ren Sai-Yan ¹ , Zhou Qi ² , Zhou He-Yang ¹ , Wang Lin-Wei ¹ , Mulina Olga M ³ , Paveliev Stanislav A ³ , Tang Hai-Tao ¹ , Terentʼev Alexander O ³ , Pan Ying-Ming ¹ , Meng Xiu-Jin ¹

Affiliations

1	State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People’s Republic of China
2	Adesis Inc. A Universal Display Company, New Castle, Delaware 19720, United States
3	Russian Acad Sci, Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia

Azoles and organoselenium compounds are pharmacologically important scaffolds in medicinal chemistry and natural products. We developed an efficient regioselective electrochemical aminoselenation reaction of 1,3-dienes, azoles, and diselenide derivatives to access selenium-containing allylazoles skeletons. This protocol is more economical and environmentally friendly and features a broad substrate scope; pyrazole, triazole, and tetrazolium were all tolerated under the standard conditions, which could be applied to the expedient synthesis of bioactive molecules and in the pharmaceutical industry.

Ren S-Y. , Zhou Q. , Zhou H-Y. , Wang L-W. , Mulina O.M. , Paveliev S.A. , Tang H-T. , Terentʼev A.O. , Pan Y-M. , Meng X-J.
Three-Component Electrochemical Aminoselenation of 1,3-Dienes
Journal of Organic Chemistry. 2023. V.88. N9. P.5760-5771. DOI: 10.1021/acs.joc.3c00214 WOS Scopus OpenAlex

Web of science:	WOS:000969191000001
Scopus:	2-s2.0-85152141437
OpenAlex:	W4362706111

DB	Citing
OpenAlex	14
Scopus	13
Web of science	12