Sciact
  • EN
  • RU

Three-Component Electrochemical Aminoselenation of 1,3-Dienes Full article

Journal Journal of Organic Chemistry
ISSN: 1520-6904 , E-ISSN: 0022-3263
Output data Year: 2023, Volume: 88, Number: 9, Pages: 5760-5771 Pages count : 12 DOI: 10.1021/acs.joc.3c00214
Authors Ren Sai-Yan 1 , Zhou Qi 2 , Zhou He-Yang 1 , Wang Lin-Wei 1 , Mulina Olga M 3 , Paveliev Stanislav A 3 , Tang Hai-Tao 1 , Terentʼev Alexander O 3 , Pan Ying-Ming 1 , Meng Xiu-Jin 1
Affiliations
1 State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People’s Republic of China
2 Adesis Inc. A Universal Display Company, New Castle, Delaware 19720, United States
3 Russian Acad Sci, Zelinsky Inst Organ Chem, 47 Leninsky Prosp, Moscow 119991, Russia

Abstract: Azoles and organoselenium compounds are pharmacologically important scaffolds in medicinal chemistry and natural products. We developed an efficient regioselective electrochemical aminoselenation reaction of 1,3-dienes, azoles, and diselenide derivatives to access selenium-containing allylazoles skeletons. This protocol is more economical and environmentally friendly and features a broad substrate scope; pyrazole, triazole, and tetrazolium were all tolerated under the standard conditions, which could be applied to the expedient synthesis of bioactive molecules and in the pharmaceutical industry.
Cite: Ren S-Y. , Zhou Q. , Zhou H-Y. , Wang L-W. , Mulina O.M. , Paveliev S.A. , Tang H-T. , Terentʼev A.O. , Pan Y-M. , Meng X-J.
Three-Component Electrochemical Aminoselenation of 1,3-Dienes
Journal of Organic Chemistry. 2023. V.88. N9. P.5760-5771. DOI: 10.1021/acs.joc.3c00214 WOS Scopus OpenAlex
Identifiers:
Web of science: WOS:000969191000001
Scopus: 2-s2.0-85152141437
OpenAlex: W4362706111
Citing:
DB Citing
OpenAlex 17
Scopus 13
Web of science 17
Altmetrics: