Synthesis of 1-arylcytosine-5-carboxylic acid esters | Sciact - научная деятельность

Synthesis of 1-arylcytosine-5-carboxylic acid esters Научная публикация

Журнал

Russian Chemical Bulletin
ISSN: 1573-9171 , E-ISSN: 1066-5285

Вых. Данные

Год: 2010, Том: 59, Номер: 5, Страницы: 1035-1040 Страниц : 6 DOI: 10.1007/s11172-010-0201-5

Авторы

Dorokhov V.A. ¹ , Voronkova V.A. ¹ , Komkov A.V. ¹ , Baranin S.V. ¹ , Vasil’ev L.S. ¹

Организации

1	N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

A reaction of alkyl 2-(diaminomethylidene)-3-oxoalkanoates with arylisocyanates leads to the formation of the corresponding ureas, which upon the action of Na alkoxides cyclize to 1-aryl-6-R-cytosine-5-carboxylates. The latter reacting with arylisocyanates according to the similar scheme give rise to 3,6-diaryl-5-methylpyrimido[4,5-d]pyrimidine-2,4,7(1H,3H,6H)-triones.

Dorokhov V.A. , Voronkova V.A. , Komkov A.V. , Baranin S.V. , Vasil’ev L.S.
Synthesis of 1-arylcytosine-5-carboxylic acid esters
Russian Chemical Bulletin. 2010. V.59. N5. P.1035-1040. DOI: 10.1007/s11172-010-0201-5 WOS Scopus OpenAlex

≡ Web of science:	WOS:000284320500023
≡ Scopus:	2-s2.0-78650140506
≡ OpenAlex:	W2024303800