Nucleophilic Halogenation of Heterocyclic N‐Oxides: Recent Progress and a Practical Guide

Nucleophilic Halogenation of Heterocyclic N‐Oxides: Recent Progress and a Practical Guide Обзор

Журнал

Advanced Synthesis & Catalysis
ISSN: 1615-4169 , E-ISSN: 1615-4150

Вых. Данные

Год: 2021, Том: 363, Номер: 13, Страницы: 3170-3188 Страниц : 19 DOI: 10.1002/adsc.202100284

Авторы

Malykhin Roman S. ^1,2 , Sukhorukov Alexey Yu. ^2,3

Организации

1	M. V. Lomonosov Moscow State University Department of Chemistry Leninskie gory, 1, str. 3 Moscow 119991 Russian Federation
2	N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences Leninsky prospect, 47 Moscow 119991 Russia
3	Plekhanov Russian University of Economics Stremyanny per. 36 Moscow 117997 Russia

The review summarizes recent advances in the synthesis of C2-halogenated nitrogen heterocycles via nucleophilic halogenation of corresponding N-oxides as well as application of this methodology in the synthesis of pharmaceuticals. Both scientific and patent literature is reviewed mostly over the period of the last ten years. The review contains a practical guide (typical procedures and infographic based on extensive literature analysis), which can help practitioners in choosing optimal reagents/conditions for nucleophilic halogenation of N-heterocycles of different types. The bibliography contains 199 references.

Malykhin R.S. , Sukhorukov A.Y.
Nucleophilic Halogenation of Heterocyclic N‐Oxides: Recent Progress and a Practical Guide
Advanced Synthesis & Catalysis. 2021. V.363. N13. P.3170-3188. DOI: 10.1002/adsc.202100284 WOS Scopus OpenAlex

Web of science:	WOS:000645463900001
Scopus:	2-s2.0-85105351182
OpenAlex:	W3154348823

БД	Цитирований
OpenAlex	29
Scopus	28
Web of science	28