The electrocatalytic cascade assembling of isatins, malononitrile and N-alkyl barbiturates: An efficient multicomponent approach to the spiro[indole-3,5′-pyrano[2,3-d]pyrimidine] framework Full article
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Electrochimica Acta
ISSN: 1873-3859 , E-ISSN: 0013-4686 |
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| Output data | Year: 2008, Volume: 53, Number: 28, Pages: 8346-8350 Pages count : 5 DOI: 10.1016/j.electacta.2008.06.044 | ||
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Abstract:
Electrochemically induced catalytic multicomponent transformation of isatins, barbituric acid or N-alkyl barbiturates and malononitrile in alcohols in an undivided cell results in the formation of substituted 7′-amino-2,2′,4′-trioxo-1,1′,2,2′,3′,4′-hexahydrospiro[indole-3,5′-pyrano[2,3-d]pyrimidine]-6′-carbonitriles in 80–95% yields. The developed efficient electrocatalytic approach to corresponding spiro[indole-3,5′-pyrano[2,3-d]pyrimidine] system is beneficial from the viewpoint of diversity-oriented large-scale processes and represents a new example of the ecologically pure synthetic concept for electrocatalytic multicomponent reactions strategy.
Cite:
Elinson M.N.
, Ilovaisky A.I.
, Merkulova V.M.
, Demchuk D.V.
, Belyakov P.A.
, Ogibin Y.N.
, Nikishin G.I.
The electrocatalytic cascade assembling of isatins, malononitrile and N-alkyl barbiturates: An efficient multicomponent approach to the spiro[indole-3,5′-pyrano[2,3-d]pyrimidine] framework
Electrochimica Acta. 2008. V.53. N28. P.8346-8350. DOI: 10.1016/j.electacta.2008.06.044 WOS Scopus OpenAlex
The electrocatalytic cascade assembling of isatins, malononitrile and N-alkyl barbiturates: An efficient multicomponent approach to the spiro[indole-3,5′-pyrano[2,3-d]pyrimidine] framework
Electrochimica Acta. 2008. V.53. N28. P.8346-8350. DOI: 10.1016/j.electacta.2008.06.044 WOS Scopus OpenAlex
Identifiers:
| Web of science: | WOS:000259835300035 |
| Scopus: | 2-s2.0-50649095467 |
| OpenAlex: | W2076439346 |