Efficient acid-promoted per-O-sulfation of organic polyols

Efficient acid-promoted per-O-sulfation of organic polyols Full article

Journal

Tetrahedron Letters
ISSN: 0040-4039 , E-ISSN: 1873-3581

Output data

Year: 2008, Volume: 49, Number: 41, Pages: 5877-5879 Pages count : 3 DOI: 10.1016/j.tetlet.2008.07.135

Authors

Krylov Vadim B. ¹ , Ustyuzhanina Nadezhda E. ¹ , Grachev Alexey A. ¹ , Nifantiev Nikolay E. ¹

Affiliations

1	N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky prospect 47, 119991 Moscow B-334, Russia

An efficient protocol for the preparation of per-O-sulfated organic compounds is reported. Sulfation of polyols with the Et3N·SO3 complex in DMF in the presence of triflic acid allowed acceleration of the reaction at lower temperature. The efficiency of the developed protocol is demonstrated by the transformation of a series of organic polyols and phenols related to oligosaccharides, cyclitols, lignans and flavonoids.

Krylov V.B. , Ustyuzhanina N.E. , Grachev A.A. , Nifantiev N.E.
Efficient acid-promoted per-O-sulfation of organic polyols
Tetrahedron Letters. 2008. V.49. N41. P.5877-5879. DOI: 10.1016/j.tetlet.2008.07.135 WOS Scopus OpenAlex

≡ Web of science:	WOS:000259595100011
≡ Scopus:	2-s2.0-50149089065
≡ OpenAlex:	W2076938417